Research
All research activity is undertaken by dedicated staff, who have received ICH-GCP training. Activity is regularly monitored by the trials sponsors and the MHRA, who made a routine inspection of PHT in 2011.
The department operates within the clinical governance structure of PHT with regular minuted morbidity and mortality meetings and within the Trust’s risk reporting system. Our department has an exemplary rolling annual audit programme, and all clinical audits are registered with the PHT audit dept.
Patients and family members may be approached by one of our research team to ask if our patientwould like to be considered for participation in a study. You will be provided with information and the opportunity to ask questions and take time to consider these discussions. You are under no obligation to do this but we offer this to all our patients where they meet the eligibility criteria for studies that we are involved with. Details of studies we are currently involved with and previous ones are recorded below:
Current research studies
CALORIES - Early enteral vs parenteral nutrition in critical illness. UKCLRN funded.
Previous studies
OSCAR - High frequency Oscillation vs conventional ventilation in severe hypoxaemic respiratory failure.
TracMan - HTA funded multicentre trial of early vs late tracheostomy on survival and length of stay.
Prowess Shock - Commercially sponsored multicentre international study of activated protein C vs placebo in early stage septic shock, plus proteomics sub study.
EASE - environmental monitoring of airborne samples HPA run.
European Surgical Outcomes Study - UKCLRN funded point prevalence study.
FIRE Fungal Infection Risk Evaluation - UKCLRN funded.
iCanUK Intensive care follow up identification study.
SwiFT Swine Flu Surveillance 2009/10 UKCLRN funded.
USII Surveillance of unidentified pathogens for the HPA.
Future studies
VANISH - In set up, due to open Feb 2012. Vasopressin vs Noradrenaline in septic shock.
FIRST Faecal Incontinence reassessment study 2012, in set up. Commercially funded.
The department operates within the clinical governance structure of PHT with regular minuted morbidity and mortality meetings and within the Trust’s risk reporting system. Our department has an exemplary rolling annual audit programme, and all clinical audits are registered with the PHT audit dept.
Patients and family members may be approached by one of our research team to ask if our patientwould like to be considered for participation in a study. You will be provided with information and the opportunity to ask questions and take time to consider these discussions. You are under no obligation to do this but we offer this to all our patients where they meet the eligibility criteria for studies that we are involved with. Details of studies we are currently involved with and previous ones are recorded below:
Current research studies
CALORIES - Early enteral vs parenteral nutrition in critical illness. UKCLRN funded.
Previous studies
OSCAR - High frequency Oscillation vs conventional ventilation in severe hypoxaemic respiratory failure.
TracMan - HTA funded multicentre trial of early vs late tracheostomy on survival and length of stay.
Prowess Shock - Commercially sponsored multicentre international study of activated protein C vs placebo in early stage septic shock, plus proteomics sub study.
EASE - environmental monitoring of airborne samples HPA run.
European Surgical Outcomes Study - UKCLRN funded point prevalence study.
FIRE Fungal Infection Risk Evaluation - UKCLRN funded.
iCanUK Intensive care follow up identification study.
SwiFT Swine Flu Surveillance 2009/10 UKCLRN funded.
USII Surveillance of unidentified pathogens for the HPA.
Future studies
VANISH - In set up, due to open Feb 2012. Vasopressin vs Noradrenaline in septic shock.
FIRST Faecal Incontinence reassessment study 2012, in set up. Commercially funded.
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